' 
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 10 Reviews
8.7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Thiamin (as thiamine hydrochloride)
25 mg
2,083%
Riboflavin (as riboflavin 5'-phosphate sodium)
20 mg
1,538%
Niacin (as inositol hexanicotinate and nicotinic acid)
95 mg NE
594%
Vitamin B6 (as pyridoxal 5'-phosphate)
20 mg
1,176%
Folate [as Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt and calcium folinate]
680 mcg DFE (400 mcg)
170%
Vitamin B12 (as MECOBALACTIVE® methylcobalamin and adenosylcobalamin)
50 mcg
2,083%
Biotin
750 mcg
2,500%
Pantothenic Acid (as d-calcium pantothenate)
125 mg
2,500%
Choline (as choline bitartrate)
50 mg
9%
Top Medical Research Studies
7
B12 and folic acid show variability
Response to vitamin B12 and folic acid in myalgic encephalomyelitis and fibromyalgia.
Moderate relevance in chronic fatigue
We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Read More
Most Useful Reviews
10
Increased energy
I don't feel tired after taking this product. I feel full of vitality and a burst of energy. There is no better remedy for fatigue than this.
Read More
9.5
Substantial benefits
This complex greatly helped with fatigue, hair loss, lack of appetite, and vitamin B deficiency from tests. I purchased it on my nutritionist friend's advice. The size is small, the taste is neutral. I take it once a day, and it’s convenient. My health has improved significantly. Thank you for this organic product; it’s worth the price.
Read More
8.8
Improved vitality
I was interested in supplements from this manufacturer, and I am very pleased that iHerb carries them. I used to take B Complex from another brand, but it wasn't the ideal range of ingredients, so I stopped. I am grateful this product has met my expectations. I occasionally felt pain due to fatigue and stress, but after starting this, I became more positive and woke up feeling refreshed. With my nervous disposition, I recommend it if you’re similar.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
- All Researches
7
B12 and folic acid show variability
Response to vitamin B12 and folic acid in myalgic encephalomyelitis and fibromyalgia.
Moderate relevance in chronic fatigue
We examined the effects of vitamin B12 injections, combined with folic acid, on 38 patients with myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Participants were split into "Good" and "Mild" responders based on their improvement. Good responders reported greater progress with more frequent injections and higher doses of both supplements.
However, for Mild responders, the improvement was limited, suggesting that while there is potential for benefit, the response can vary widely among individuals. Overall, further investigation is needed to explore optimal treatment strategies.
Read More
User Reviews
USERS' SCORE
Good
Based on 10 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
10
Increased energy
I don't feel tired after taking this product. I feel full of vitality and a burst of energy. There is no better remedy for fatigue than this.
9.5
Substantial benefits
This complex greatly helped with fatigue, hair loss, lack of appetite, and vitamin B deficiency from tests. I purchased it on my nutritionist friend's advice. The size is small, the taste is neutral. I take it once a day, and it’s convenient. My health has improved significantly. Thank you for this organic product; it’s worth the price.
Read More
8.8
Improved vitality
I was interested in supplements from this manufacturer, and I am very pleased that iHerb carries them. I used to take B Complex from another brand, but it wasn't the ideal range of ingredients, so I stopped. I am grateful this product has met my expectations. I occasionally felt pain due to fatigue and stress, but after starting this, I became more positive and woke up feeling refreshed. With my nervous disposition, I recommend it if you’re similar.
Read More
8.3
Significant improvement
Pure Composition was prescribed by my nutritionist, and it's often out of stock—so when I find it, I buy immediately. The vitamin B2, B6, and B12 in coenzyme form are excellent, and the dosages are mostly good. My condition has improved significantly; homocysteine normalised, and my headaches and fatigue have disappeared.
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8.8
Chronic fatigue alleviated
I bought this because my body lacks active B vitamins. A genetic test confirmed my inability to synthesise them, and regular B vitamins don't suffice. For those like me, it's essential to consume products containing active vitamin B, such as Complex Plus. Taking this has significantly improved my condition. Other efforts have also contributed.
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